RESEARCH USE ONLY

Plans for the teams taking on rare cancers.

The same engine behind every tier. What changes between them is how much of it you can point at once, who is allowed to use it, and whether a named person stands behind the answer. A hypothesis generator and prioritisation engine, not a diagnostic.

PRICING

One ladder, from a free benchmark to a named programme.

An academic lab pays per lab, with no seat count, because a research group loses and gains people by design. A commercial buyer pays per seat, or per team with seats included. A programme is one named indication or target, agreed in a project plan, time-boxed, and expandable only by amendment. Research use only: a hypothesis generator and prioritisation engine, not a diagnostic and not a medical device.

Provisional pricing. These numbers are set from published comparables and are not settled. Expect them to move.

Checkout is not open, so nothing here can be bought today and no card is taken anywhere on this site.

Free

Anyone deciding whether Onkydra can answer their question at all.

€0free forever

One seat.

Academic lab

One named academic lab, where no for-profit owns the intellectual property in the work.

€300per lab

€249 a month billed yearly.

No seat count.

Commercial seat

One named person at a company, or an academic on a programme whose IP a for-profit owns.

€800per seat

€664 a month billed yearly.

One seat.

Commercial team

A rare-cancer R&D team running more than one candidate at a time.

€1,600per team

€1,328 a month billed yearly.

3 seats included. €300 a month per extra seat.

Programme

A team betting the next twelve to eighteen months on one target or one indication.

Quotedfrom €40,000 per year
What changes at each step

This lists what DIFFERS between two adjacent tiers, in both directions: a commercial seat covers one person where an academic lab covers a whole group, and that shows up here as the reduction it is.

FreeAcademic lab
  • Indications in scopeRead-only, on the public benchmark H3 K27M DMG, within its stated scope
  • Runs of your ownNot included Included
  • Daily run ceiling4 a day 5 a day
  • Targets under watchNone 3 targets
  • Mechanistic in-silico knockoutNot included Included

and 8 more differences in the table below.

Academic labCommercial seat
  • People includedUnlimited, in one named lab 1 named user
  • Commercial use of the outputNot included Included
  • Where questions goEmail Email, plus an onboarding walkthrough
  • Invoice and purchase-order billingNot included Included
  • Data-processing agreementTemplate published Counter-signed

and 1 more difference in the table below.

Commercial seatCommercial team
  • Daily run ceiling5 a day 15 a day
  • Targets under watch3 targets 10 targets
  • People included1 named user 3, then a flat rate for each extra
  • Shared programme memoryNot included In build, not live
  • Where questions goEmail, plus an onboarding walkthrough Email, onboarding, and a quarterly programme review

and 2 more differences in the table below.

Commercial teamProgramme
  • Indications in scopeH3 K27M DMG, within its stated scope DMG, plus one named indication or target curated for you
  • Runs of your ownIncluded Agreed in the project plan
  • Daily run ceiling15 a day Agreed in the project plan
  • Targets under watch10 targets Agreed in the project plan
  • An indication or target curated for youNot included Included

and 7 more differences in the table below.

Full comparison

Every line, on every tier.

Monthly rates below. Annual billing is 17% off on every tier that has a monthly rate, on the toggle above. Nothing on this page can be bought today.

What you can analyse
  • Indications in scope

    One indication is wired today: H3 K27M diffuse midline glioma, on an n=60 anchor pooled from DKFZ and CPTAC via cBioPortal, with 13 driver features and no treatment-response or survival layer. It runs within that stated scope. Every other indication is on the roadmap and the coverage gate refuses it rather than guessing.

    Free
    Read-only, on the public benchmark
    Academic lab
    H3 K27M DMG, within its stated scope
    Commercial seat
    H3 K27M DMG, within its stated scope
    Commercial team
    H3 K27M DMG, within its stated scope
    Programme
    DMG, plus one named indication or target curated for you
  • Coverage check before you commit

    Ask whether Onkydra can answer about a target in an indication and get yes or no with the reason for a no. It is the same gate the run path uses, so a refusal here is the refusal you would get in a run. Available without paying anything, deliberately.

    Free
    Included
    Academic lab
    Included
    Commercial seat
    Included
    Commercial team
    Included
    Programme
    Included
  • Runs of your own

    The free tier grants zero compute. That is the step up to any paid tier and there is no softer way to say it.

    Free
    Not included
    Academic lab
    Included
    Commercial seat
    Included
    Commercial team
    Included
    Programme
    Agreed in the project plan
  • Daily run ceiling

    A ceiling on spend, not a price basis. Nothing is sold by the run: there is no top-up, no credit pack and no consumable anywhere in checkout, and an exhausted ceiling sells you nothing and waits for the 24-hour window to roll. An abstention is metered on its own counter at three times the allowance, so an honest refusal is never the expensive answer.

    Free
    4 a day
    Academic lab
    5 a day
    Commercial seat
    5 a day
    Commercial team
    15 a day
    Programme
    Agreed in the project plan
  • Targets under watch

    One slot is one target watched inside one investigation, which is a standing commitment to check evidence on your behalf. The watching itself, weekly re-runs and drift alerts when ClinVar, the dependency rows or the literature move, is in build and is live on no tier today.

    Free
    None
    Academic lab
    3 targets
    Commercial seat
    3 targets
    Commercial team
    10 targets
    Programme
    Agreed in the project plan
  • Mechanistic in-silico knockout

    Real CellOracle knockouts over a DMG regulatory network, served for 45 transcription factors and for ACVR1 through an explicitly labelled bridge to its downstream factors. It abstains for everything else, which is why CDK7, MEK1, PI3K, ONC201 and MENIN get no mechanistic prediction. An uncalibrated ordering signal and never a probability. Identical on every paid tier.

    Free
    Not included
    Academic lab
    Included
    Commercial seat
    Included
    Commercial team
    Included
    Programme
    Included
  • Measured screen evidence

    Pooled CRISPR dependency in the six DMG lines from the Childhood Cancer Model Atlas deposit, and 1,430 transcription factors measured in DIPG17 from GSE267415. A screen measures what a cell needs in order to proliferate, which is a different question from what controls its state, and every surface serving one says so. Identical on every paid tier.

    Free
    Not included
    Academic lab
    Included
    Commercial seat
    Included
    Commercial team
    Included
    Programme
    Included
  • Tumour-tile morphology description

    MedGemma describes the morphology of an H&E tile: cellularity, nuclear features, architecture. It is asked for a description and never for a diagnosis, a grade or a subtype, and the prompt is fixed server-side so it cannot be asked for one.

    Free
    Not included
    Academic lab
    Included
    Commercial seat
    Included
    Commercial team
    Included
    Programme
    Included
  • An indication or target curated for you

    Curating an indication means building and verifying its anchor cohort, its regulatory network and its screen evidence, then stating what is missing. It is scoped work with a project plan behind it, which is why it is not a monthly add-on at any subscription tier.

    Free
    Not included
    Academic lab
    Not included
    Commercial seat
    Not included
    Commercial team
    Not included
    Programme
    Included
Evidence and provenance
  • Every claim resolved to a citation

    PMIDs and DOIs are resolved against NCBI and CrossRef at run time, and a citation that does not resolve does not reach the output. This is what stops a fabricated reference, and it runs on every tier including the sample report.

    Free
    Included
    Academic lab
    Included
    Commercial seat
    Included
    Commercial team
    Included
    Programme
    Included
  • Retracted sources held, not cited

    A cited paper that has been retracted holds the run rather than appearing with a footnote. This has fired on a real run.

    Free
    Included
    Academic lab
    Included
    Commercial seat
    Included
    Commercial team
    Included
    Programme
    Included
  • Evidence class declared on every layer

    Measured result, model run, stated rule, or labelled placeholder, named per layer and never upgraded by the report writer. Negative, null and uninterpretable results are preserved rather than dropped.

    Free
    Included
    Academic lab
    Included
    Commercial seat
    Included
    Commercial team
    Included
    Programme
    Included
  • Abstention when the target is out of scope

    Onkydra refuses and says why, rather than producing a confident answer about a target it has no grounded evidence for. A refused run does not consume the daily run ceiling.

    Free
    Included
    Academic lab
    Included
    Commercial seat
    Included
    Commercial team
    Included
    Programme
    Included
  • Full artefact export

    The complete run artefact, including inputs, tool calls, evidence classes and citations, exportable as JSON so a result can leave the product and be checked by somebody who does not have an account.

    Free
    Not included
    Academic lab
    Included
    Commercial seat
    Included
    Commercial team
    Included
    Programme
    Included
  • Intervals resampled over the real anchor

    Every interval is bootstrapped over the 60 real cases, never over the simulated draws. A simulated co-mutation profile is a Monte Carlo draw from one fitted model and is never a patient, which is also why nothing here is ever priced by how many of them a run makes.

    Free
    Included
    Academic lab
    Included
    Commercial seat
    Included
    Commercial team
    Included
    Programme
    Included
The experiment
  • Prediction frozen before the result is known

    The prediction ledger writes a claim, its evidence and its date before anybody knows the answer, so it cannot be edited to fit the outcome afterwards. The ledger is real and no prediction has been resolved yet, because no result has come back.

    Free
    Not included
    Academic lab
    Included
    Commercial seat
    Included
    Commercial team
    Included
    Programme
    Included
  • The experiment designed with us

    On the subscription tiers you decide what to test and you carry the interpretation. On a programme the experiment is specified in the project plan with us before it runs, which is the difference between a tool you operate and an answer somebody stands behind.

    Free
    Not included
    Academic lab
    Not included
    Commercial seat
    Not included
    Commercial team
    Not included
    Programme
    Included
  • Observed result filed against the prediction

    The result that comes back goes into the immutable record against the prediction that preceded it, whether it agrees or not. Resolution is built and has never run, because nobody has returned a result yet, and this table will say so until one does.

    Free
    Not included
    Academic lab
    Self-filed
    Commercial seat
    Self-filed
    Commercial team
    Self-filed
    Programme
    Filed with us, against the project plan
  • A named person accountable for the answer

    The credence-goods literature is the honest framing here: you cannot verify this kind of answer even after delivery, and the two things that make such a market work are liability and verifiability. The subscription tiers sell capability, so you carry the risk of having used it wrongly. The programme tier sells somebody standing behind the answer. Different jobs, which is what makes the multiple coherent instead of insulting.

    Free
    Not included
    Academic lab
    Not included
    Commercial seat
    Not included
    Commercial team
    Not included
    Programme
    Included
Collaboration and seats
  • People included

    The academic tier is priced per lab rather than per person because a research group of three to fifteen churns people by design, and two 10-K filings in this sector state plainly that seat pricing shrinks when a customer loses staff. Charging a lab for that is charging it for being a lab.

    Free
    1
    Academic lab
    Unlimited, in one named lab
    Commercial seat
    1 named user
    Commercial team
    3, then a flat rate for each extra
    Programme
    Agreed in the project plan
  • Shared programme memory

    IN BUILD, LIVE ON NO TIER. The workspace is single-user today and there is no team or seat model behind it. It is listed because it is what the team tier is for, and it is marked because nobody should buy it expecting it this month.

    Free
    Not included
    Academic lab
    Not included
    Commercial seat
    Not included
    Commercial team
    In build, not live
    Programme
    In build, not live
  • Commercial use of the output

    The academic tier is fenced on employer and IP ownership rather than on an email domain. Work inside your employment at a for-profit, and contract research where a for-profit owns the intellectual property, both need a commercial licence even when the person doing it sits in a university.

    Free
    Not included
    Academic lab
    Not included
    Commercial seat
    Included
    Commercial team
    Included
    Programme
    Included
Support
  • Where questions go

    All customer-facing founder time comes out of one weekly ceiling, and support and scientific authoring draw on the same hours. The ceiling is a stated decision rather than a measurement, because there are no customers to measure. It is published so that a promise this product cannot keep is visible before you buy rather than after.

    Free
    Public docs and the capability register
    Academic lab
    Email
    Commercial seat
    Email, plus an onboarding walkthrough
    Commercial team
    Email, onboarding, and a quarterly programme review
    Programme
    A named contact, inside the project plan
  • Founder time is capped, and the cap is published

    Five hours a week of customer-facing founder time, in total, across every customer. A ceiling and not a target, and it exists because the alternative failure is invisible: hours quietly leaving the research one reasonable half-hour at a time.

    Free
    Included
    Academic lab
    Included
    Commercial seat
    Included
    Commercial team
    Included
    Programme
    Included
Procurement
  • Card, monthly, cancel anytime

    Monthly billing keeps every transaction under the university purchasing-card limits observed across the institutions checked ($2,500 to $5,000) and under both stated purchase-order floors, so the purchase never has to touch procurement. Watch one clause if you are at a US university: at least one bars services from the card entirely, at any amount.

    Free
    Included
    Academic lab
    Included
    Commercial seat
    Included
    Commercial team
    Included
    Programme
    Not included
  • Annual billing at a discount

    Seventeen percent off the monthly rate, billed yearly. It clears the academic purchase-order floor on purpose, for a buyer who would rather pass through procurement once a year than expense a card charge every month.

    Free
    Not included
    Academic lab
    Included
    Commercial seat
    Included
    Commercial team
    Included
    Programme
    Annual by default
  • Invoice and purchase-order billing

    The honest upgrade gate for a small commercial buyer. It is not a feature anybody wants: it is something their organisation demands, which is exactly why single sign-on works as a gate for larger vendors and cannot work here, since a solo PI and a three-person team have no identity provider to ask.

    Free
    Not included
    Academic lab
    Not included
    Commercial seat
    Included
    Commercial team
    Included
    Programme
    Included
  • Data-processing agreement

    The standard template and the sub-processor register are published and readable by anyone. A counter-signed agreement, and a customer-specific annex where one is needed, come with a commercial licence.

    Free
    Template published
    Academic lab
    Template published
    Commercial seat
    Counter-signed
    Commercial team
    Counter-signed, with an annex where needed
    Programme
    Counter-signed, with an annex where needed
  • Security questionnaire completed

    We complete your questionnaire, including the HECVAT that several US universities require before any software is acquired, free items and renewals included. None has been completed yet, because no customer has asked for one.

    Free
    Not included
    Academic lab
    Not included
    Commercial seat
    On request
    Commercial team
    Included
    Programme
    Included
  • Validated-system documentation

    NOT OFFERED AT ANY TIER, and it is in this table so that nobody assumes it comes with the largest one. Onkydra is a hypothesis generator and a prioritisation engine, research use only, and it makes no 21 CFR part 11 or EU Annex 11 claim. If your process needs a validated system, this is not one.

    Free
    Not included
    Academic lab
    Not included
    Commercial seat
    Not included
    Commercial team
    Not included
    Programme
    Not included
  • Research use only

    Not a diagnostic, not a medical device, not a treatment recommender, and not a substitute for wet-lab validation. This does not change at any price, and a tier that relaxed it would be selling something Onkydra is not.

    Free
    Included
    Academic lab
    Included
    Commercial seat
    Included
    Commercial team
    Included
    Programme
    Included
Indication roadmap

Cohort packs: which indication should we build next?

Every plan ships with the DMG anchor cohort. Diffuse midline glioma is the only indication live today, and it runs within a stated scope: an n=60 anchor, 13 driver features, and no outcome layer. The rest are on the roadmap in the order below. Curating an indication means licensing and validating a whole molecular-profile library, so it is scoped as a programme rather than a monthly add-on. Tell us which one you need and it moves up the queue.

Tell us which one →
  • Diffuse midline glioma

    Included

    H3 K27M anchor, n=60, DKFZ + CPTAC

    Included

  • Ewing sarcoma

    In the queue

    EWSR1 fusion, adolescent + young-adult anchor

    Roadmap

  • MPNST

    In the queue

    NF1-driven, malignant peripheral nerve sheath

    Roadmap

  • ATRT

    In the queue

    SMARCB1 loss, atypical teratoid rhabdoid

    Roadmap

  • High-risk neuroblastoma

    In the queue

    MYCN-amplified, paediatric

    Roadmap

  • Anaplastic thyroid

    In the queue

    BRAF V600E, TP53 co-mutation

    Roadmap

  • Rhabdomyosarcoma

    In the queue

    PAX-FOXO1 fusion, paediatric

    Roadmap

  • Pediatric AML (KMT2Ar)

    In the queue

    KMT2A-rearranged, infant + paediatric

    Roadmap

A pack leaves the queue once its anchor cohort has been curated and validated end-to-end through the run pipeline. Diffuse midline glioma is the only pack live today, and it runs within a stated scope. Every other indication listed here is roadmap, not shipped, and ships in order.

Monthly by default

Billed monthly, cancel anytime, no lock-in. Annual is 17% off and is a choice rather than the default, because a monthly transaction is a small one.

Nothing is for sale yet

Checkout is not open. No card is taken anywhere on this site, and there is no plan to manage from the workspace.

Research use only

A hypothesis and prioritisation engine. Not a diagnostic, not a treatment recommender, not a medical device.

More on trials, billing, and commercial terms in the pricing FAQ.

PRIVATE BETA

Get early access to Onkydra.

Onkydra is in private beta and the workspace is open to one address. Join the waitlist and we will reach out with a first run for your programme when it opens to biotech and research teams working on rare cancers.

No spam. We email you once, when your run is ready.

Onkydra is in private betaJoin